David Tscharke received a bachelor of science (Hons) and PhD from the University of Adelaide studying viral pathogenesis and immunology. In 1997 he began postdoctoral work in the same field, first at the University of Oxford and Imperial College in the UK and then at the US National Institutes of Health in Bethesda, MD, USA.
In 2003, David returned to Australia, working at the Queensland Institute of Medical Research in Brisbane before moving to the Australian National University in 2006 to start his own laboratory.
He was awarded a Young Tall Poppy Science Award and Agilent Technologies Award for Life Science by the Australian Institute for Policy and Science in 2006 and an NHMRC Career Development Award in 2007.
Since 2012 he has been an ARC Future Fellow. His current research interests revolve around gain a better understanding of viruses and how viral infections are controlled by the immune system, including how we can exploit this knowledge to improve vaccines.